Glutaraldehyde, formula C5H8O2, colorless, transparent, oily liquid with pungent odor, soluble in hot water. It has a strong irritating effect on eyes, skin and mucous membranes. Can be used as food processing aids, bacteria disinfectants, tanning agents, wood preservatives, pharmaceuticals and high-molecular synthetic raw materials, etc.
Chinese name: glutaraldehyde
Chinese alias: glutaraldehyde, solution;
English name: Glutaric dialdehyde
English name:Glutaraldehyde Solution BP;Pentanedial;1,5-Pentanedial;glutaraldehyde sol,FEM,~50% in H2O;glutaraldehyde sol,for EM,~25% in H2O;glutaraldehyde grade I;glutaraldehyde 50% aqueous solution*photographic; Glutaraldehyde grade I 50% aqueous*solution;glutaraldehyde grade I 70% aqueous*solution;Glutaraldehyde, 25% Aqueous Solution;Glutaraldehyde 50% solution;Glutarldehyde;Glutaraldehyde
CAS No.: 111-30-8
Molecular formula: C5H8O2
Molecular weight: 100.1158
Physical and chemical properties
Appearance and traits: Colorless or light yellow transparent oily liquid with slightly pungent odor.
Melting point: -5°C
Boiling point: 189°C at 760 mmHg
Flash point: 66°C
Relative vapor density (air = 1): 3.4
Steam pressure: 0.583mmHg at 25°C
Solubility: soluble in organic solvents such as hot water, ethanol, chloroform, glacial acetic acid, and ether.
Storage and transportation characteristics: warehouse ventilation and low temperature drying; separate storage with oxidants, food additives,
Uses: Sterilizers, tanning agents, wood preservatives, drugs and raw materials for polymer synthesis.
Combustibility Hazardous properties Aqueous solution is not flammable; Heat released to liberate gas flammable; Fire field emits spicy smoke
Storage and storage characteristics Storeroom ventilation and low temperature drying; Store separately from oxidants and food additives
Extinguishing agent Foam, carbon dioxide, sand
Professional Standard TWA 0.8 mg/m3; STEL 1.2 mg/m³
Dangerous goods sign T, N, Xn
Hazard category code 36/37/38-42/43-34-23-22-50-23/25-41-37/38-20/22
Safety instructions 23-26-36/37-45-36/37/39-61
Dangerous goods transportation number UN 2922 8/PG 2
WGK Germany 3
RTECS number MA2450000
Poisonous Substances Data 111-30-8 (Hazardous Substances Data)
Health hazards: Harmful if inhaled, ingested, or absorbed through the skin. It has a strong irritating effect on eyes, skin and mucous membranes. Inhalation can cause throat, bronchial inflammation, chemical pneumonia, pulmonary edema, and so on. This product can cause allergic reactions.
Environmental hazards: Harm to the environment and cause pollution to water bodies.
Explosion hazard: This product is flammable, strong irritant.
Dangerous characteristics: In the event of fire, high heat flammable. Contact with strong oxidants can occur chemically. Its vapour is heavier than air, and it can spread to relatively far places in the lower places. It will burn in the event of fire. It is easy to self-aggregate and the polymerization reaction sharply increases with increasing temperature. In case of high heat, the internal pressure of the container increases, causing cracking and explosion.
Occupational protection: Glutaraldehyde can cause local skin and mucous membrane irritation, and has been reported to cause allergic contact dermatitis, asthma, nosebleeds, rhinitis, etc. Therefore, when exposed to glutaraldehyde solution, thick rubber gloves and goggles should be worn to prevent liquid splashing. Into the eye. In order to reduce the concentration of glutaraldehyde in the indoor air, there must be well ventilated equipment in the room; a partial exhaust hood should be provided above the container containing glutaraldehyde, and the solution must be covered in a timely manner to prevent build-up and removal of the product. Dialdehyde evaporated. Frequent exposure to special populations of glutaraldehyde, such as nurses, can cause sensitization in the short-term and cause greater damage to the visual organs and respiratory tract. Occupational asthma can occur over time.
[Use 1] Sterilizers, tanning agents, wood preservatives, drugs and high-molecular synthetic raw materials.
[Use 2] As a fixing agent for microscope inspection
[Use 3] Combining with chrome to make cow, pig, sheep garment leather and glove leather. It should be sealed at low temperatures (below 0°C) and protected from light. This product has strong irritation to the eyes and skin, and should wear glasses, gloves and other protective equipment. Cannot be mixed with phenolic plant tanning agents and synthetic tanning agents.
[Use 4] Glutaraldehyde is a kind of low-toxic chemical antiseptic fungicide. It can be used for the preservation of vegetables and fruits in China. The maximum amount used is 0.05g/kg, and the residual amount is not more than 5mg/kg.
[Use 5] Glutaraldehyde is used for disinfecting, pharmacy, tanning, and as a hardener for electron microscopes and color picture tubes. The product is used to produce the central stimulant, proanthroine hydrochloride. Glutaraldehyde is a fast-acting, broad-spectrum chemical sterilizing agent. Its low concentration of glutaraldehyde can exhibit activity against many microorganisms at room temperature, and it can be used to breed bacteria, viruses, mycobacteria and pathogenicity. Mold and bacterial spores have a high degree of sterilizing effect, and the toxicity to humans is very low. Some people claim that formaldehyde was used at the beginning of this century, and chemical disinfectants such as ethylene oxide were used in the 1930s. At present, glutaraldehyde is the third milestone. In 1973, the World Health Organization (WHO) deposited three products as disinfectants for hepatitis B virus. Among the known aldehydes, glutaraldehyde is one of the best protein cross-linking agents. Cross-linking is characterized by high activity, fast reaction, high binding amount, stable product, and strong resistance to boiling water, acids and enzymes. The leather tanned with glutaraldehyde has excellent properties such as sweat resistance, heat resistance, soaping resistance and the like.
[Use 6] Glutaraldehyde is regarded as the third milestone in the history of the development of chemical disinfectants after the disinfection of formaldehyde and ethylene oxide. As a raw material for producing glutaraldehyde series bactericides, glutaraldehyde (111-30-8) series bactericides have the characteristics of low methanol content, no variability and no toxic accumulation, and are widely used in sterilization, sterilization and pharmaceutical industries. .
Glutaraldehyde (111-30-8) is a highly effective disinfectant, with a broad spectrum, high efficiency, low toxicity, little corrosive to metals, less affected by organic matter, and good stability. It is suitable for disinfection and sterilization of medical instruments and moisture-proof heat-resistant precision instruments. Its sterilizing concentration was 2%, and glutaraldehyde was mainly sold in the following manner: 2% basic glutaraldehyde and 2% enhanced acid glutaraldehyde. Alkaline glutaraldehyde is commonly used for sterilization of medical devices. The amount of sodium bicarbonate should be added before use. Shake well and let stand for 1 hour to determine the pH. At pH 7.5-8.5, glutaraldehyde has the strongest bactericidal effect.
Glutaraldehyde bactericidal (111-30-8) is the function of its monomers. When the pH of the solution reaches 6, these monomers have the tendency to polymerize. With the increase of pH, the polymerization is extremely rapid, and the solution can be precipitated. , After the formation of polymer will lose its bactericidal effect. Therefore, basic glutaraldehyde is a relatively unstable disinfectant, and 2% fortified glutaraldehyde is a polyoxyethylene fatty alcohol ether as a fortifier, which can enhance the bactericidal effect of glutaraldehyde. Its pH is lower than 5, and it is weaker than alkaline glutaraldehyde in the killing effect on bacterial spores, but it is more effective than alkaline glutaraldehyde in the inactivation of viruses, and its stability is better than that of basic glutaraldehyde, and can be used continuously. 28 days.
[Use 7] Glutaraldehyde is the most important saturated straight-chain aliphatic dibasic aldehyde after glyoxal. Glutaraldehyde is regarded as the third generation of chemical sterilizing agent, and it is also an excellent tanning agent, protein cross-linking agent, efficient bactericidal disinfectant, biological enzyme and cell tissue curing agent. Widely used in medicine, health, petrochemical, light industry and scientific research.